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Which of the following is a secondary sexual characteristic regulated by estrogen?

  1. Growth of facial hair

  2. Development of mammary glands

  3. Deepening of the voice

  4. Increased muscle mass

The correct answer is: Development of mammary glands

The development of mammary glands is indeed a secondary sexual characteristic regulated by estrogen. During puberty, estrogen plays a crucial role in the growth and development of breast tissue, allowing for the physical changes associated with female sexual maturation. This includes the formation of milk-producing glands and the overall increase in breast size, which are key indicators of sexual maturity in females. Other characteristics mentioned, such as the growth of facial hair, deepening of the voice, and increased muscle mass, are primarily influenced by androgens. These male hormones become more prominent during puberty and are responsible for developing male secondary sexual characteristics. In contrast, estrogen is more closely related to the development of female characteristics, with the mammary glands being a prominent example of this effect.